Neural stem cells isolated from the subventricular zone of an adult C57BL/6 mouse. see the article by Gadadhar et al.

Research

Research interests of the faculty focus on specific problems in cellular and systems neuroscience (including development, aging, control of behavior, glial cell function, sensory systems and mechanisms of synaptic and ion channel functions) and cell biology (including cytoskeleton, synapse, neuron, lens and endothelium).  

 

Dr. Scott T. Brady
Professor and Head, Anatomy and Cell Biology
Research Interests: Cellular and molecular neuroscience: Research focuses on molecular motors, axonal transport and the neuronal cytoskeleton, Neuronal signaling pathways, Effects of myelin on neurons and pathogenic mechanisms in adult-onset neurodegenerative diseases including Huntington’s, Parkinson’s and Alzheimer’s disease as well as amyotrophic lateral sclerosis and diabetic neuropathy.

Office: Room 578 CME
Phone: (312) 996-6791
E-mail address:

Jonathan J. Art, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: Cochlear Hair Cell Physiology, Confocal Laser Microscopy

OPffice: Room 509 CMW
Phone: (312) 996-4956
E-mail address:

Ernesto R. Bongarzone, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: 1) Cellular Biology of Myelination, Oligodendrogenesis and Neurogenesis in the Mammalian Central Nervous System.  2) Molecular Mechanisms of Dying Back Axonopathies Associated to Myelin Disorders, Neurodegeneration and Aging.  3) Biodynamics of neural cell responses through membrane microdomains. 

Office: Room 7093 COMRB
Phone: (312) 996-6894
E-mail address:

Maria Irene Givogri, Ph.D.
Research Assistant Professor, Anatomy and Cell Biology
Research Interests: Cellular and Molecular control of oligodendrogenesis in health and disease.

Office: Room 7051 COMRB
Phone: (312) 413-1072
E-mail address:

Naohiko Ikegaki, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: Biology of Neuroblastoma

Office: Room 6035 COMRB
Laboratory: Room 6040 COMRB
Laboratory Phone: (312) 355-1012
E-mail address:

Mary Jo LaDu, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: Adult-onset Neurodegeneration. Specifically, our lab studies the structure/function interactions between apolipoprotein-E4, the primary genetic risk factor for Alzheimer's disease (AD) and beta-amyloid peptide, the only genetic causative factor for AD. We study neurotoxicity and glial-mediated inflammation with techniques including protein biophysics, biochemistry, and cell biology, also using in vitro and several unique transgenic mouse models.

Office: Room 7091 COMRB
Laboratory: Room 7060 COMRB
Office Phone: 312-355-4795
E-mail address:

Orly Lazarov, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: Cellular and molecular mechanisms underlying Alzheimer's disease; The cross talk between neurogenesis and Alzheimer's disease pathology; Stem cell therapeutics for the treatment of neurodegenerative diseases.

Office: Room 7053 COMRB
Laboratory:
Office Phone: (312) 355-0548
E-mail address:

Anna Lysakowski, Ph.D.
Professor, Anatomy and Cell Biology
Research Interests: Vestibular Physiology, Structure and Function

Office: Room 6055 COMRB
Phone: (312) 996-5990
E-mail address:

Gerardo Morfini, Ph.D.
Assistant Professor, Anatomy and Cell Biology
Research Interests: Kinase-dependent signaling mechanisms in neurons. Fast axonal transport mechanisms in health and disease.

Office: Room 6051 COMRB
Phone: (312) 996-6869
E-mail address:

Adrienne Rogalski-Wilk, Ph.D.
Associate Professor, Anatomy and Cell Biology
Research Interests: Cell and molecular biology of non-protrusive plasma membrane macrodomains associated with peripheral actin cytoskeleton networks; study of novel cell surface polarity protein complexes and their downstream signalling pathways.

Office: Room 680 CME
Office Phone: (312) 996-0130
Laboratory Phone: (312) 996-9444
E-mail address:

Kamal Sharma, Ph.D.
Visiting Associate Professor, Anatomy and Cell Biology
Research Interests: Nervous system controls how and when an animal walks, runs, breathes, lies down to rest and falls asleep. A neural network controls each of these behaviors. Our goal is to understand how these neural networks develop in the embryo and neonates, map the location of its constituent neurons and to determine how changes in these neural networks correlate with diseases such as Parkinson's and sleep apnea.

Office: Room 666 CME
Office Phone: (312) 413-0072
Laboratory Phone: (312) 355-3893
E-mail address: kamalsha@uic.edu

Xao X. Tang, Ph.D.
Assistant Professor, Anatomy and Cell Biology
Research Interests: Favorable Neuroblastoma Genes and Molecular Therapeutics of Neuroblastoma

Office: Room 6035 COMRB
Laboratory: Room 6040 COMRB
Laboratory Phone: (312) 355-1012
E-mail address:

Wolf, William A
Adjunct Professor
Research Interests: The central focus of research in my lab is on understanding adaptive changes in neuronal function ("neural plasticity") associated with psychiatric and neurologic disorders (currently Parkinson's disease, substance abuse and stroke). Understanding this neural plasticity allows us to develop pharmacotherapy targeted toward "reinstating" normal brain function or compensating for aberrant brain signaling.

Hines VA Hospital
Phone: 708-202-8387
E-mail address:

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Featured Research

Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain
by Archana Gadadhar

read paper >

Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations
by Katherine Lynn Youmans

read paper >

Disruption of Fast Axonal Transport Is a Pathogenic Mechanism for Intraneuronal Amyloid Beta
by Gustavo Pigino, PhD.

read paper >